内容简介：
This special issue of the "Journal of Neuro-oncology" provides a state-of-the-art review of the general understanding of the process of tumour invasion. In addition, the articles emphasize specific aspects of aggressive brain cancers which are particularly important for deriving new insights for therapeutic approaches for advanced brain cancer that will target tumour invasiveness. The ideas discussed are designed to stimulate further studies directed towards the translation of these important invasion-related studies to clinical approaches for the effective treatment of brain cancer.