内容简介：
This volume, the proceedings of the International Falk Symposium held in Marburg, Germany, in January 1992, summarizes the most recent advances in the study of cellular and molecular mechanisms of fibrosis provided by contributions from scientists in this field. It aims to update knowledge on the basic components of fibrosis, on the cellular origin and degradation of matrix components, on peptide and non-peptide mediators, cellular co-operation and other mechanisms of fibrogenesis, on the role of the extracellular matrix as modulator of fibrogenesis, and on some aspects of antifibrotic trials and biochemical monitoring of the development of fibrosis. Since liver fibrogenesis has, to a certain extent, attained the status of a model for fibrotic tissue reactions that occur generally in various organs and tissues, the fundamental processes described here may be relevant for other sites of tissue repairs and fibrosis, for wound healing and for atherogenesis.