内容简介：
The liver is the central organ in the metabolism and detoxification of many endogenous compounds. Recent studies have led to a better understanding of the pathways of uptake, transport, conjugation and biliary excretion of metabolites. This book, the proceedings of the 75th Falk Symposium held in Maastricht, The Netherlands, presents progress in basic science in this field and the direct application of this knowledge to treatment of hepatobiliary diseases, such as primary biliary cirrhosis, primary sclerosing cholangitis and gallstone disease. This book should provide both research scientists and clinicians with all the information on cholestatic and hepatobiliary disease currently available.