内容简介:
Presenting an extensive review of different aspects of heart-cell communication, this work begins with the fundamental concept that cardiac cells are communicated. It then proceeds to the role of gap junctions in heart development, the molecular biology of gap junctions, the biophysics of the intercellular channels, the control of junctional conductance, and the influence of gap junctions on impulse propagation. By describing, in a single volume, cell communication in the normal heart and under different pathological conditions such as heart failure, coronary disease, myocardial ischemia and cardiac arrhythmias, the book analyzes the process of cell communication at different levels of complexity, providing the reader with a wide view of this field and its relevance to cardiology.