内容简介：
This conference proceedings covers an exceptionally wide range of subjects in computational science, from astrophysics to molecular science and from general-purpose high-performance computers to special-purpose computing devices. The unique nature of this book is that the main topic is the interaction between the requirement from application and the design of high-performance computers. In particular, special-purpose computers for molecular dynamics, Lattice QCD, and astrophysics are discussed. This book will be of interest to astrophysicists, physicists and chemists who are involved in computer simulation. It will also be of interest to computer scientists with interest in hardware architecture of high-performance computers.